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Senior Director, Finance Transformation

Vertex Pharmaceuticals Incorporated
paid time off, 401(k)
United States, Massachusetts, Boston
50 Northern Avenue (Show on map)
Jan 15, 2026

Job Description

General Summary:

The Senior Director, Finance Transformation is a key member of the Vertex Global Finance organization and will be leading transformational workstreams including projects aimed at improvement of Global Finance processes, implementation and enhancement of finance systems and support of enterprise reporting capabilities.

Reporting to the VP, Global Process Excellence, Finance Systems and Reporting, this role is a key leader in ensuring that Vertex's global finance teams can scale efficiently to meet the needs of an increasingly large and complex pipeline by optimizing global processes, implementing and enhancing finance systems and building new scalable global capabilities to enable efficient and effective enterprise planning and reporting. An important aspect of this role is the ability to have influence without authority, and to be able to maintain an enterprise-wide view where global processes and solutions are most effective and efficient for Vertex. In addition, this role leads a team of finance professionals to partner with the broad finance organization to understand and assess complex process, data and reporting gaps, make recommendations on new ways of working, and lead and/or facilitate projects to implement identified solutions.

Success in this role requires a deep understanding of Vertex's business and strategy including a strong understanding of the drug development process, experience in designing and implementing complex global processes and finance systems, and an ability to lead and manage change. The best candidate will be able to collaborate effectively within Finance and with other key cross-functional stakeholders and leaders to ensure strategic and operational alignment. In addition to the Finance organization, collaboration and strong partnership with business teams including R&D, Manufacturing & Supply Chain, Commercial and the PPM organization is paramount to success in this role.

Key Duties & Responsibilities

  • Strategizes with finance and business leaders to identify and prioritize global process, data and technology optimization opportunities to enable Vertex's efficient growth through industry-leading cross-functional innovation and business partnering, and managing the roadmap of these priorities.
  • Partners with Finance leadership to develop a strategy for our Finance organization's efficient scaling in the short term and ensuring team readiness for working in a world of rapidly advancing technology.
  • Builds and manages a high-performing team that meets increasing needs and requirements across the business, helps drive the overall organization forward and has an inclusive atmosphere.
  • Strong leadership, communication, and collaboration skills to partner with senior leaders and execute on multiple projects and deliverables simultaneously.
  • Supports VRTX growth by using data and technology platforms to enable operating efficiencies, growth and ability to scale with sustainable, compliant and risk balanced processes.
  • Leads process, data and systems enhancement workstreams to help optimize the use of data driven insights to drive integrated enterprise decision making.
  • Champions VRTX global financial data structures to ensure that we are organizing and governing data to enable effective performance management and decision support as Vertex grows in scale and complexity.
  • Partners closely with Finance, PPM, HR, Accounting and DTE to ensure that Vertex is building integrated enterprise planning capabilities to enable short- and long-term decision making and resource allocation.
  • Collaborates and communicates effectively with others, identifies opportunities where change management is needed and helps to develop plans of action to address the gaps.
  • Helps to develop and coach global finance team members to encourage growth and new opportunities and maintaining an atmosphere of inclusivity across the team.
  • Utilizes data analytics and metrics to identify trends, make recommendations and mitigate resourcing and financial risks.

Basic Requirements:

  • Bachelor's degree in business, Finance or Accounting.
  • MBA and CPA a plus.
  • Typically requires a number of years of relevant experience in a finance managerial role demonstrating strong technical and analytical skills and a track record of success working in a team-based environment or the equivalent combination of education and experience. Must have a deep understanding of financial systems, expertise in analytics and presentation/visualization of information and a strategic vision of future ways of working for finance professionals.

Preferred Knowledge/Skills:

  • A continuous improvement mindset, constantly interrogating the way we operate with flexibility and ability to drive change.
  • Extensive experience in leading cross-functional teams and processes; able to manage through ambiguity and influence with and without authority, and work effectively with senior leaders
  • Significant experience in change management including identifying stakeholders, understanding change impacts, developing impactful communications and training materials, and post-change support.
  • Highly skilled in building/developing/leading a high performing team.
  • Experience partnering with cross-functional teams and processes; able to manage through ambiguity and influence with and without authority.
  • Must have vision for the future, an ability to think strategically on getting alignment across various groups, and an ability to partner effectively with Finance & Accounting leadership.
  • Ability to find innovative solutions to complex problems, leveraging industry best practices and finding solutions that are fit-for-purpose for Vertex but also contemplate future business needs.
  • Ability to effectively work with and influence senior leaders including the DTE LT, FLT, HR LT and PPM LT individually and in gaining alignment amongst these groups when needed.
  • Strong interpersonal, written, and verbal communication skills.
  • Significant knowledge of drug development process with strong business acumen and judgment; knowledge of the company's markets/products a plus.
  • Experience leveraging Lean and Six Sigma concepts to identify opportunities for improvement and to develop and implement action plans.
  • Strong project management ability and ability to manage multiple projects and areas of ownership.
  • Proactive, organized, and comfortable managing shifting priorities in a rapidly changing environment.
  • Broad and comprehensive understanding of different business systems, processes and theories.

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Pay Range:

$212,000 - $318,000

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

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Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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