Entry Laboratory Science Professional

Job Summary:

A position as an Entry Laboratory Science Professional is available within the Mosimann research laboratory in the Department of Pediatrics, Section of Developmental Biology, at the University of Colorado Anschutz Medical Campus. This is a full-time (1.0 FTE) position that will utilize molecular, biochemical, genetic, imaging, and bioinformatic/computational approaches in a wet lab setting.

The Mosimann Lab studies the formation of the heart, blood, and blood vessels, as well as their developmentally related cell types, using zebrafish as the principal model. As a Laboratory Sciences Professional in our lab, you will work closely with graduate students and postdoctoral fellows to support their projects and pursue individual lines of research. The work is highly flexible and variable, including standard molecular biology techniques (PCR, subcloning, gel electrophoresis), microscopy (fluorescence and confocal microscopy), transgenesis techniques, and basic computational/bioinformatic analyses. Commensurate with increased expertise, you will be given the opportunity to work more independently on projects using state-of-the-art methods such as scRNAseq and scMultiome analyses, transgenesis, CRISPR-Cas9, and more.

Key Responsibilities:

• Collaborate with and support Principal Investigators (PI) and other stakeholders with laboratory and research functions.

• Utilize a variety of laboratory techniques required for research projects.

• Perform experiments, tabulate, and analyze research.

• Provide animal care related to research studies, as necessary.

• Pick up, transport, and maintain results, samples, documents, materials, and other items as needed.

• Dispose of laboratory materials and samples using well-established guidelines and instructions.

• Review, complete, and process logs, documents, databases, and related materials and information.

• Review and implement lab support policies, practices, and programs to meet organizational, operations, and management needs.

• Ensure compliance with applicable laws, rules, and regulations; receive guidance and direction or escalate when required.

• Perform collaborative experiments using molecular cloning, PCR, microinjection, fluorescent and colorimetric in situ RNA hybridization, immunofluorescence, immunohistochemistry, sample sectioning, and confocal/light sheet microscopy.

• Collect data from microscopy images using imaging software such as ImageJ and Imaris and perform appropriate statistical tests.

• Keep detailed records of zebrafish stocks and experimental data.

• Write reports contributing to research summaries and manuscripts.

• Help prepare data and figures for grant proposals.

Work Location:

Onsite - this role is expected to work onsite and is located in Aurora, CO.

Why Join Us:

The Mosimann research group is part of a highly cohesive, productive academic unit in the Section of Developmental Biology within the Department of Pediatrics. The Section of Developmental Biology is committed to research that improves child health with five main objectives:

Understand the genetic, molecular, and cellular mechanisms that guide normal development.

Determine how normal developmental processes are altered to result in developmental disease and disability.

Identify new diagnostic strategies and molecular and cellular therapies targeted at the treatment of childhood disease.

Train the next generation of leaders in developmental and stem cell biology and pediatric disease research.

Serve as a hub for basic and translational child health research that spans the Anschutz Medical Campus research community.

Why work for the University?

We have AMAZING benefits and offer exceptional amounts of holiday, vacation, and sick leave! The University of Colorado offers an excellent benefits package, including:

• Medical: Multiple plan options

• Dental: Multiple plan options

• Additional Insurance: Disability, Life, Vision

• Retirement 401(a) Plan: Employer contributes 10% of your gross pay

• Paid Time Off: Accruals over the year

• Vacation Days: 22/year (maximum accrual 352 hours)

• Sick Days: 15/year (unlimited maximum accrual)

• Holiday Days: 15/year

• Tuition Benefit: Employees have access to this benefit on all CU campuses

• ECO Pass: Reduced-rate RTD Bus and light rail service

There are many additional perks & programs with the CU Advantage.

Qualifications:

Minimum Qualifications:

• Bachelor's degree in biology, molecular biology, chemistry, genetics, or a related field.

Applicants must meet minimum qualifications at the time of hire.

Applicants must be legally authorized to work in the United States without requiring sponsorship. We are unable to provide work visa sponsorship or employment authorization for this position now or in the future.

Preferred Qualifications:

• Master's degree in biology, molecular biology, chemistry, genetics, or a related field.

• experience with aseptic technique and culture of cell lines, primary cells, pluripotent stem cells, and/or 3D organoids.

• Experience with cellular and molecular biology techniques (DNA/RNA isolation, PCR/qPCR, electrophoresis, molecular cloning, immunostaining, FACS, etc.).

• Experience with microscopy and/or fluorescence imaging.

• Experience with CRISPR/Cas9 based gene editing.

Knowledge, Skills, and Abilities:

• Knowledge of basic laboratory techniques, including safety procedures and techniques.

• Ability to communicate effectively, both in writing and orally.

• Ability to establish and maintain effective working relationships with employees at all levels throughout the institution.

• Outstanding customer service skills.

• Knowledge of basic human anatomy, physiology, and medical terminology.

• Ability to interpret and master complex research protocol information.

How to Apply:

For full consideration, please submit the following document(s):

1. A letter of interest describing relevant job experiences as they relate to the listed job qualifications and interest in the position

2. Curriculum vitae / Resume

3. Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address

Questions should be directed to: Christian Mosimann, Christian.Mosimann@cuanschutz.edu

Screening of Applications Begins:

Immediately and continues until five (5) days after the posting date.

Anticipated Pay Range:

The starting salary range (or hiring range) for this position has been established as $47,811 to $60,816.

The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation, depending on the level.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans, and retirement contributions that add to your bottom line.

Total Compensation Calculator

Equal Employment Opportunity Statement:

CU is an Equal Opportunity Employer and complies with all applicable federal, state, and local laws governing nondiscrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity, and we encourage individuals from all backgrounds to apply, including protected veterans and individuals with disabilities.

ADA Statement:

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@cuanschutz.edu.

Background Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students, and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

Vaccination Statement:

CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine-preventable diseases. If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety-sensitive job duties, you must enroll in the occupational health medical surveillance program.