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The Laboratory of Dr Xiaoyan Zheng in the Department of Anatomy and Cell Biology and the Cancer Center at the George Washington University School of Medicine and Health Sciences seeks a highly motivated Postdoctoral Associate. Our primary research interest is in identifying target genes regulated by the Hh signal and thus to understand the molecular mechanisms employed by the Hh signaling pathway in regulating cell-cell interactions (I). In parallel, we are interested in developing novel reagents and experimental approaches combined with cutting-edge imaging technologies to study the biochemical and cell biological principles governing a critical yet poorly understood step of Hh signal transduction: trafficking of Hh receptors (II). These studies have broad potential significance for our understanding of the molecular basis of both development and human diseases linked to Hh pathway dysfunction, as well as for providing a basis for therapeutic modulation of pathway activity, either positively to stimulate regeneration or negatively to block malignant growth.
In the Zheng Lab, the postdoctoral associate will design, organize, and conduct specialized and advanced experiments using established scientific protocols, troubleshoot and design new protocols, summarize findings and publish results in research journals, under the general supervision of a faculty member. In some cases, postdocs will assume general responsibility for general scientific operations in the lab, and/or provide supervision and guidance to laboratory staff, trainees and other researchers.
Duties include:
- Design and implement research protocols; design safety procedures; adapt new procedures, methods or instrumentation relative to research procedures.
- Collect, prepare and analyze research data; keep a detailed notebook summarizing experiments and recording research data; maintain computer database of research data; tabulate and display data for presentation in research conferences and for manuscript preparation; use graphics and statistical software to analyze and present data; search pertinent scientific literature as needed.
- Supervise other personnel in the laboratory; participate in training of fellows, residents, students and volunteer workers as needed.
- Oversee reagent preparation, equipment maintenance, animal maintenance; assist with ordering and procurement and with general maintenance of laboratory.
In collaboration with experienced researchers, this role will participate in the planning and conduction of discovery research, data analysis and interpretation, preparation of materials for publication, presentations at conferences and meetings, and may develop new theories and methodologies. This role can expect timely advice as to research directions and career planning for a future independent career.
A Postdoctoral Associate:
* holds a PhD or equivalent degree;
* develops skills by participating in scholarly projects that are actively mentored by a member of the university faculty;
* receives financial support in the form of a salary that is typically funded by grants, contracts or departmental funds secured by a faculty mentor; and
* has a limited term of up to five years at GW.
In collaboration with experienced researchers, this role will participate in the planning and conduction of discovery research, data analysis and interpretation, preparation of materials for publication, presentations at conferences and meetings, and may develop new theories and methodologies. This role can expect timely advice as to research directions and career planning for a future independent career.
Performs other related duties as assigned. The omission of specific duties does not preclude the supervisor from assigning duties that are logically related to the position.
Special Instructions to the Applicant:
Appointments are limited-term and are designed for those who have recently received a doctorate. Appointments are made to academic departments with the approval of the department head and may require senior officer approval. Appointments are usually for not less than one term and are normally not renewed beyond a total of five years. This appointment is not intended for long-term, indefinite, or career appointments. |
George Washington University
Dec 24, 2024