Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 72 |
Cambridge, Massachusetts
Overview The Research Department at Alnylam is seeking a scientist to contribute to our targeted delivery efforts for expanding RNAi into new tissues. The candidate will contribute to platform efforts centered on extrahepatic siRNA delivery...
8h
| Job Type | Full Time |
Senior Associate Scientist, In Vivo Pharmacology
Cambridge, Massachusetts
Overview The Research Department at Alnylam is seeking a passionate and motivated Senior Associate Scientist to join our dynamic, fast-paced and interdisciplinary in vivo Pharmacology team within the RNAi Discovery Platform group. The succe...
8h
| Job Type | Full Time |
Vice President, HR Business Partner, R&D
Cambridge, Massachusetts
OVERVIEW: Reporting to the Chief Human Resources Officer, the Vice President, Human Resources for R&D will lead the global people and culture strategy for Alnylam's Research & Development organization. As a key member of the HR Leadership T...
14h
| Job Type | Full Time |
Business Account Executive, TTR - San Antonio, TX
Cambridge, Massachusetts
Overview We are looking for experienced Business Account Executives (BAEs) with specialty sales experience to promote AMVUTTRA. hATTR patients often spend years undiagnosed and misdiagnosed. This is an amazing opportunity to educate and enh...
21h
| Job Type | Full Time |
Senior Scientist, Statistical Genetics
Cambridge, Massachusetts
Overview The Alnylam Human Genetics (AHG) team is looking for a passionate and driven scientist to apply human genetics to drug discovery and development. The successful candidate will perform comprehensive analyses of human genetic data to...
2d
| Job Type | Full Time |
Cambridge, Massachusetts
Overview: The Director, Specification will be responsible for leading release and stability specifications development according to control strategy for Alnylam clinical programs. A successful candidate will be accountable for authoring and...
3d
| Job Type | Full Time |
Director, General & Administrative (G&A) Finance
Cambridge, Massachusetts
Overview: The Director of G&A Finance is a strategic and highly visible finance leader responsible for managing the financial performance and planning for the Chief Financial Officer's (CFO) organization. This includes working closely with ...
3d
| Job Type | Full Time |
Senior Associate Scientist, Histology
Cambridge, Massachusetts
Overview We are seeking a highly motivated Senior Associate Scientist to join our Histology team. The ideal candidate will bring hands-on experience in a histology laboratory and a strong understanding of anatomy and standard histology proc...
3d
| Job Type | Full Time |
Senior Director, IT - Finance/ERP
Cambridge, Massachusetts
Overview: We are seeking a strategic, results-driven IT leader to own the technology vision and execution for Finance and the SAP Center of Excellence. The leader of financial systems is responsible for a wide range of functions and systems...
4d
| Job Type | Full Time |
Executive Director, Pharmacometrics
Cambridge, Massachusetts
Overview Seeking an experienced Head of Pharmacometrics to expand Clinical Pharmacology and Pharmacometrics capabilities within Alnylam. The Executive Director, Pharmacometrics is a on-site, leadership role focused on providing strategic di...
4d
| Job Type | Full Time |